2. Protein Tyrosine Kinase/RTK PI3K/Akt/mTOR
  3. FAK Akt
  4. 123060-40-2

123060-40-2

1-Myristoyl-2-hydroxy-sn-glycero-3-phosphoethanolamine Chemical Structure

123060-40-2

Chemical Structure

  • 1-Myristoyl-2-hydroxy-sn-glycero-3-phosphoethanolamine
  • Synonym(s): 14:0 Lyso PE; 1-Myristoyl-2-hydroxy-sn-glycero-3-PE; 1-Tetradecanoyl-sn-glycero-3-phosphoethanolamine
  • CAS No: 123060-40-2
    Formula: C19H40NO7P
    Molecular Weight: 425.50
  • IUPAC Name: (2R)-3-(((2-aminoethoxy)(hydroxy)phosphoryl)oxy)-2-hydroxypropyl tetradecanoate
  • InChIKey: RPXHXZNGZBHSMJ-GOSISDBHSA-N
  • SMILES: CCCCCCCCCCCCCC(OC[C@@H](O)COP(OCCN)(O)=O)=O

Biological Activity: 1-Myristoyl-2-hydroxy-sn-glycero-3-phosphoethanolamine (14:0 Lyso PE) is a lysophospholipid with a phosphoethanolamine head and a myristoyl tail. The free amine group can conjugate with NHS active ester or coupled with carboxylic acid in the presence of a coupling agent. It also induces transient increases in intracellular calcium in PC12 cells [1]. Serum levels of 1-Myristoyl-2-hydroxy-sn-glycero-3-phosphoethanolamine are elevated in patients with malignant breast cancer compared to healthy controls[2].

Cat. No. Product Name Purity Description
HY-Y0607S 4-Nitrobenzoic acid-d4 4-Nitrobenzoic acid-d4 is the deuterium labeled 4-Nitrobenzoic acid (HY-Y0607).
HY-Y0607 4-Nitrobenzoic acid 99.84% 4-Nitrobenzoic acid is a kind of biological materials or organic compounds that are widely used in life science research.
HY-Y0607R 4-Nitrobenzoic acid (Standard) ≥98% 4-Nitrobenzoic acid (Standard) is the analytical standard of 4-Nitrobenzoic acid. This product is intended for research and analytical applications. 4-Nitrobenzoic acid is a kind of biological materials or organic compounds that are widely used in life science research.

References

[1]. Lee, J.M., Park, S.J., and Im, D.S. Lysophosphatidylethanolamine increases intracellular Ca2+ through LPA1 in PC-12 neuronal cells. Biochem. Biophys. Res. Commun. 461(2), 378-382 (2015). [Content Brief]
[2]. More, T.H., Bagadi, M., RoyChoudhury, S., et al. Comprehensive quantitative lipidomic approach to investigate serum phospholipid alterations in breast cancer. Metabolomics 13:3, (2017).

Keywords:

1-Myristoyl-2-hydroxy-sn-glycero-3-phosphoethanolamine