2. Anti-infection
  3. Fungal Antibiotic
  4. 92121-68-1

92121-68-1

Obafluorin Chemical Structure

92121-68-1

Chemical Structure

  • Obafluorin
  • CAS No: 92121-68-1
    Formula: C17H14N2O7
    Molecular Weight: 358.30
  • IUPAC Name: 2,3-dihydroxy-N-((2R,3S)-2-(4-nitrobenzyl)-4-oxooxetan-3-yl)benzamide
  • InChIKey: AINNQKIVZOTQBB-KGLIPLIRSA-N
  • SMILES: O=C(C(C=CC=C1O)=C1O)N[C@H](C2=O)[C@H](O2)CC(C=C3)=CC=C3[N](=O)=O

Biological Activity: Obafluorin is a β-Lactone Antibiotic, that can be produced by Pseudomonas fluorescens ATCC 39502. Obafluorin exhibits antibacterial activity against a range of Gram-positive and Gram-negative bacteria. Obafluorin fully inhibits E. coli threonyl-tRNA synthetase[1].

Cat. No. Product Name Purity Description
HY-138075 Obafluorin Obafluorin is a β-Lactone Antibiotic, that can be produced by Pseudomonas fluorescens ATCC 39502. Obafluorin exhibits antibacterial activity against a range of Gram-positive and Gram-negative bacteria. Obafluorin fully inhibits E. coli threonyl-tRNA synthetase.

References

[1]. Scott TA, et al. Immunity-Guided Identification of Threonyl-tRNA Synthetase as the Molecular Target of Obafluorin, a β-Lactone Antibiotic. ACS Chem Biol. 2019 Dec 20;14(12):2663-2671. [Content Brief]

Keywords:

Obafluorin