2. Peptides
  3. Reagents for Peptide Synthesis
  4. Amino acids and Derivatives
  5. 3934-84-7

3934-84-7

3-O-Methylgallic acid Chemical Structure

3934-84-7

Chemical Structure

  • 3-O-Methylgallic acid
  • Synonym(s): 3,4-Dihydroxy-5-methoxybenzoic acid
  • CAS No: 3934-84-7
    Formula: C8H8O5
    Molecular Weight: 184.15
  • IUPAC Name: 3,4-dihydroxy-5-methoxybenzoic acid
  • InChIKey: KWCCUYSXAYTNKA-UHFFFAOYSA-N
  • SMILES: O=C(O)C1=CC(OC)=C(O)C(O)=C1

Biological Activity: 3-O-Methylgallic acid (3,4-Dihydroxy-5-methoxybenzoic acid) is an anthocyanin metabolite and has potent antioxidant capacity. 3-O-methylgallic acid inhibits Caco-2 cell proliferation with an IC50 value of 24.1 μM. 3-O-methylgallic acid also induces cell apoptosis and has anti-cancer effects[1][2][3].

Cat. No. Product Name Purity Description
HY-N2009 3-O-Methylgallic acid 99.22% 3-O-Methylgallic acid (3,4-Dihydroxy-5-methoxybenzoic acid) is an anthocyanin metabolite and has potent antioxidant capacity. 3-O-methylgallic acid inhibits Caco-2 cell proliferation with an IC50 value of 24.1 μM. 3-O-methylgallic acid also induces cell apoptosis and has anti-cancer effects.

References

[1]. Forester SC, et al. Gut metabolites of anthocyanins, gallic acid, 3-O-methylgallic acid, and 2,4,6-trihydroxybenzaldehyde, inhibit cell proliferation of Caco-2 cells. J Agric Food Chem. 2010 May 12;58(9):5320-7. [Content Brief]
[2]. Forester SC, The anthocyanin metabolites gallic acid, 3-O-methylgallic acid, and 2,4,6-trihydroxybenzaldehyde decrease human colon cancer cell viability by regulating pro-oncogenic signals. Mol Carcinog. 2014 Jun;53(6):432-9. [Content Brief]
[3]. Gargouri OD, et al. Synthesis of 3-O-methylgallic acid a powerful antioxidant by electrochemical conversion of syringic acid. Biochim Biophys Acta. 2013 Jun;1830(6):3643-9. [Content Brief]

Keywords:

3-O-Methylgallic acid