1. Cell Cycle/DNA Damage
  2. CDK
  3. 2922069-42-7

2922069-42-7

HH0043 Chemical Structure

2922069-42-7

Chemical Structure

  • HH0043
  • CAS No: 2922069-42-7
    Formula: C23H24F3N5O
    Molecular Weight: 443.46
  • InChIKey: GSZLBBQYAQRWAD-CQSZACIVSA-N
  • SMILES: CC(N(CC1)CCN1C2=CC(C(N[C@H](C)C3=CC=CC(C(F)F)=C3F)=CC=N4)=C4C=N2)=O

Biological Activity: HH0043 (Compound 10f) is an orally active and potent SOS1 inhibitor, with IC50 value of 5.8 nM. HH0043 can be used for the research of cancer[1].

Cat. No. Product Name Purity Description
HY-149009 Bcl-2-IN-9 Bcl-2-IN-9 is a novel proapoptotic Bcl-2 inhibitor with IC50 value of 2.9 μM and low cytotoxic. Bcl-2-IN-9 mediates apoptosis by down-regulating expression of Bcl-2 in cancer cells and has a high selectivity against leukemia cells.

References

Keywords:

HH0043