2. Metabolic Enzyme/Protease
  3. Endogenous Metabolite
  4. 67910-12-7

67910-12-7

11-Dehydro-thromboxane B2 Chemical Structure

67910-12-7

Chemical Structure

  • 11-Dehydro-thromboxane B2
  • CAS No: 67910-12-7
    Formula: C20H32O6
    Molecular Weight: 368.46
  • IUPAC Name: (Z)-7-((2R,3S,4S)-4-hydroxy-2-((S,E)-3-hydroxyoct-1-en-1-yl)-6-oxotetrahydro-2H-pyran-3-yl)hept-5-enoic acid
  • InChIKey: KJYIVXDPWBUJBQ-UHHGALCXSA-N
  • SMILES: O=C(O)CCC/C=C\C[C@@H]([C@@H](O)C1)[C@@H](/C=C/[C@@H](O)CCCCC)OC1=O

Biological Activity: 11-Dehydro-thromboxane B2 is a platelet hemagglutinin. Thromboxane inhibition was assessed by urinary excretion levels of 11-Dehydro-thromboxane B2. 11-Dehydro-thromboxane B2 can be used in the study of atherosclerotic thrombosis[1][2].

References

[1]. Simeone P, et al. Significance of urinary 11-dehydro-thromboxane B2 in age-related diseases: Focus on atherothrombosis. Ageing Res Rev. 2018 Dec;48:51-78. [Content Brief]
[2]. Lopez LR, et al. Platelet thromboxane (11-dehydro-Thromboxane B2) and aspirin response in patients with diabetes and coronary artery disease. World J Diabetes. 2014 Apr 15;5(2):115-27. [Content Brief]

Keywords:

11-Dehydro-thromboxane B211-Dehydro-thromboxane B2-d411-Dehydro-thromboxane B2-13C5