2. MAPK/ERK Pathway Apoptosis
  3. Raf Apoptosis
  4. 72214-67-6

72214-67-6

RRD-251 Chemical Structure

72214-67-6

Chemical Structure

  • RRD-251
  • CAS No: 72214-67-6
    Formula: C8H9Cl3N2S
    Molecular Weight: 271.59
  • IUPAC Name: 2,4-dichlorobenzyl carbamimidothioate hydrochloride
  • InChIKey: COMNQRICZGJVLE-UHFFFAOYSA-N
  • SMILES: NC(SCC1=CC=C(Cl)C=C1Cl)=N.[H]Cl

Biological Activity: RRD-251 is an inhibitor of retinoblastoma tumor suppressor protein (Rb)-Raf-1 interaction, with potent anti-proliferative, anti-angiogenic and anti-tumor activities[1].

Cat. No. Product Name Purity Description
HY-117737A RRD-251 99.94% RRD-251 is an inhibitor of retinoblastoma tumor suppressor protein (Rb)-Raf-1 interaction, with potent anti-proliferative, anti-angiogenic and anti-tumor activities.

References

[1]. Sandeep Singh, et al. Rb-Raf-1 interaction disruptor RRD-251 induces apoptosis in metastatic melanoma cells and synergizes with dacarbazine. Mol Cancer Ther. 2010 Dec; 9(12): 3330–3341. [Content Brief]

Keywords:

RRD-251