2. GPCR/G Protein Neuronal Signaling
  3. Adrenergic Receptor
  4. 72877-72-6

72877-72-6

LY87130 free base Chemical Structure

72877-72-6

Chemical Structure

  • LY87130 free base
  • CAS No: 72877-72-6
    Formula: C12H13N
    Molecular Weight: 171.24
  • IUPAC Name: 2,3,4,5-tetrahydro-1H-indeno[1,2-c]pyridine
  • InChIKey: BYNLJTRLTJOKOU-UHFFFAOYSA-N
  • SMILES: C12=C(CC3=C2C=CC=C3)CCNC1

Biological Activity: LY87130 free base is an octopamine-N-methyltransferase inhibitor with epinephrine-inhibiting activity. LY87130 free base can significantly reduce the basal level of epinephrine in the hypothalamus after administration. LY87130 free base has no significant effect on the basal levels of norepinephrine, 3,4-dihydroxyphenylacetic acid (DOPAC) and 5-hydroxyindoleacetic acid (5-HIAA) in the hypothalamus[1].

Cat. No. Product Name Purity Description
HY-135242 LY87130 free base LY87130 free base is an octopamine-N-methyltransferase inhibitor with epinephrine-inhibiting activity. LY87130 free base can significantly reduce the basal level of epinephrine in the hypothalamus after administration. LY87130 free base has no significant effect on the basal levels of norepinephrine, 3,4-dihydroxyphenylacetic acid (DOPAC) and 5-hydroxyindoleacetic acid (5-HIAA) in the hypothalamus.

References

[1]. Comparison of the effects of selected drugs on the release of hypothalamic adrenaline and noradrenaline measured in vivo [Content Brief]

Keywords:

LY87130 free base