2. Membrane Transporter/Ion Channel Autophagy Anti-infection Metabolic Enzyme/Protease
  3. Proton Pump Autophagy Bacterial Phospholipase
  4. 68682-01-9

68682-01-9

(2R/S)-6-PNG Chemical Structure

68682-01-9

Chemical Structure

  • (2R/S)-6-PNG
  • Synonym(s): 6-Prenylnaringenin; (±)-6-Prenylnaringenin
  • CAS No: 68682-01-9
    Formula: C20H20O5
    Molecular Weight: 340.37
  • IUPAC Name: 5,7-dihydroxy-2-(4-hydroxyphenyl)-6-(3-methylbut-2-en-1-yl)chroman-4-one
  • InChIKey: YHWNASRGLKJRJJ-UHFFFAOYSA-N
  • SMILES: O=C1CC(C2=CC=C(O)C=C2)OC3=CC(O)=C(C/C=C(C)\C)C(O)=C13

Biological Activity: (2R/S)-6-PNG (6-Prenylnaringenin) is a potent and reversible Cav3.2 T-type Ca2+ channels (T-channels) blocker. (2R/S)-6-PNG can penetrate the blood-brain barrier (BBB). (2R/S)-6-PNG suppresses neuropathic and visceral pain in mice[1].

Cat. No. Product Name Purity Description
HY-115681 (2R/S)-6-PNG 99.88% (2R/S)-6-PNG (6-Prenylnaringenin) is a potent and reversible Cav3.2 T-type Ca2+ channels (T-channels) blocker. (2R/S)-6-PNG can penetrate the blood-brain barrier (BBB). (2R/S)-6-PNG suppresses neuropathic and visceral pain in mice.
HY-115681R (2R/S)-6-PNG (Standard) ≥98% (2R/S)-6-PNG (Standard) is the analytical standard of (2R/S)-6-PNG. This product is intended for research and analytical applications. (2R/S)-6-PNG (6-Prenylnaringenin) is a potent and reversible Cav3.2 T-type Ca2+ channels (T-channels) blocker. (2R/S)-6-PNG can penetrate the blood-brain barrier (BBB). (2R/S)-6-PNG suppresses neuropathic and visceral pain in mice.

References

[1]. Fumiko Sekiguchi, et al. Blockade of T-type calcium channels by 6-prenylnaringenin, a hop component, alleviates neuropathic and visceral pain in mice. Neuropharmacology [Content Brief]

Keywords:

(2R/S)-6-PNG(2R/S)-6-PNG (Standard)