2. GPCR/G Protein
  3. Prostaglandin Receptor
  4. 80943-40-4

80943-40-4

D,L-erythro-PDMP hydrochloride Chemical Structure

80943-40-4

Chemical Structure

  • D,L-erythro-PDMP hydrochloride
  • CAS No: 80943-40-4
    Formula: C23H39ClN2O3
    Molecular Weight: 427.02
  • IUPAC Name: N-((1S,2R)-1-hydroxy-3-morpholino-1-phenylpropan-2-yl)decanamide hydrochloride
  • InChIKey: HVJHJOYQTSEKPK-QRIJJCFISA-N
  • SMILES: O[C@@H](C1=CC=CC=C1)[C@H](NC(CCCCCCCCC)=O)CN2CCOCC2.[H]Cl

Biological Activity: D,L-erythro-PDMP hydrochloride is an erythro isomer of PDMP. D,L-erythro-PDMP hydrochloride causes growth inhibition of cultured rabbit skin fibroblasts. PDMP is an effective inhibitor of UDP-glucose:ceramide glucosyltransferase[1][2].

Cat. No. Product Name Purity Description
HY-116392H D,L-erythro-PDMP hydrochloride 99.67% D,L-erythro-PDMP hydrochloride is an erythro isomer of PDMP. D,L-erythro-PDMP hydrochloride causes growth inhibition of cultured rabbit skin fibroblasts. PDMP is an effective inhibitor of UDP-glucose:ceramide glucosyltransferase.

References

[1]. Uemura K, et al. Effect of an inhibitor of glucosylceramide synthesis on cultured rabbit skin fibroblasts. J Biochem. 1990 Oct;108(4):525-30. [Content Brief]
[2]. Abe A, et al. Induction of glucosylceramide synthase by synthase inhibitors and ceramide. Biochim Biophys Acta. 1996 Feb 16;1299(3):333-41. [Content Brief]

Keywords:

D,L-erythro-PDMP hydrochloride