2. Peptides
  3. Peptide and Derivatives
  4. Inhibitors and Substrates
  5. 6659-45-6

6659-45-6

Dihydrorotenone Chemical Structure

6659-45-6

Chemical Structure

  • Dihydrorotenone
  • CAS No: 6659-45-6
    Formula: C23H24O6
    Molecular Weight: 396.43
  • IUPAC Name: (2R,6aS,12aS)-2-isopropyl-8,9-dimethoxy-1,2,12,12a-tetrahydrochromeno[3,4-b]furo[2,3-h]chromen-6(6aH)-one
  • InChIKey: DTFARBHXORYQBF-HBGVWJBISA-N
  • SMILES: O=C1[C@]2([H])[C@](COC3=CC(OC)=C(OC)C=C32)([H])OC4=C5C(O[C@@H](C(C)C)C5)=CC=C14

Biological Activity: Dihydrorotenone, a natural pesticide, is a potent mitochondrial inhibitor. Dihydrorotenone probably induces Parkinsonian syndrome. Dihydrorotenone induces human plasma cell apoptosis by triggering endoplasmic reticulum stress and activating p38 signaling pathway[1].

Cat. No. Product Name Purity Description
HY-N4202 Dihydrorotenone 99.66% Dihydrorotenone, a natural pesticide, is a potent mitochondrial inhibitor. Dihydrorotenone probably induces Parkinsonian syndrome. Dihydrorotenone induces human plasma cell apoptosis by triggering endoplasmic reticulum stress and activating p38 signaling pathway.

References

[1]. Zhang J, et al. The natural pesticide dihydrorotenone induces human plasma cell apoptosis by triggering endoplasmic reticulum stress and activating p38 signaling pathway. PLoS One. 2013 Jul 26;8(7):e69911. [Content Brief]

Keywords:

Dihydrorotenone