2. Cytoskeleton
  3. Arp2/3 Complex
  4. 26098-04-4

26098-04-4

Gentamicin C1a Chemical Structure

26098-04-4

Chemical Structure

  • Gentamicin C1a
  • CAS No: 26098-04-4
    Formula: C19H39N5O7
    Molecular Weight: 449.54
  • IUPAC Name: (2R,3R,4R,5R)-2-(((1S,2S,3R,4S,6R)-4,6-diamino-3-(((2R,3R,6S)-3-amino-6-(aminomethyl)tetrahydro-2H-pyran-2-yl)oxy)-2-hydroxycyclohexyl)oxy)-5-methyl-4-(methylamino)tetrahydro-2H-pyran-3,5-diol
  • InChIKey: VEGXETMJINRLTH-BOZYPMBZSA-N
  • SMILES: O[C@@H]([C@@H]([C@H](C[C@H]1N)N)O[C@H]2O[C@@H](CC[C@H]2N)CN)[C@H]1O[C@@H]3[C@@H]([C@H]([C@@](O)(CO3)C)NC)O

Biological Activity: Gentamicin C1a is the precursor of the semi-synthetic antibiotic Etimicin, and has antibacterial activity. Gentamicin C1a is the major component of the Gentamicin complex[1][2].

References

[1]. Li D, et al. Construction of a gentamicin C1a-overproducing strain of Micromonospora purpurea by inactivation of the gacD gene. Microbiol Res. 2013 Jun 12;168(5):263-7. [Content Brief]
[2]. Ishikawa M, et al. Lower ototoxicity and absence of hidden hearing loss point to gentamicin C1a and apramycin as promising antibiotics for clinical use. Sci Rep. 2019 Feb 20;9(1):2410. [Content Brief]

Keywords:

Gentamicin C1a (Standard)Gentamicin C1a