1. NF-κB
  2. NF-κB
  3. 796854-35-8

796854-35-8

WAY-204688 Chemical Structure

796854-35-8

Chemical Structure

  • WAY-204688
  • Synonym(s): SIM-688
  • CAS No: 796854-35-8
    Formula: C34H31F3N2O2
    Molecular Weight: 556.62
  • IUPAC Name: (2S,3S)-3-(2-methoxyphenyl)-2-methyl-3-(naphthalen-1-yl)-2-(4-(3-(trifluoromethyl)phenyl)piperidine-1-carbonyl)propanenitrile
  • InChIKey: JZPONCMNBSEYQW-CQTOTRCISA-N
  • SMILES: COC1=C([C@H](C2=CC=CC3=C2C=CC=C3)[C@@](C)(C#N)C(N4CCC(C5=CC(C(F)(F)F)=CC=C5)CC4)=O)C=CC=C1

Biological Activity: WAY-204688 is an estrogen receptor (ER-α) selective, orally active inhibitor of NF-κB transcriptional activity with an IC50 of 122 ± 30 nM for NF-κB-luciferase (NF-κB-luc) in HAECT-1 cells.

Cat. No. Product Name Purity Description
HY-19498 WAY-204688 99.06% WAY-204688 is an estrogen receptor (ER-α) selective, orally active inhibitor of NF-κB transcriptional activity with an IC50 of 122 ± 30 nM for NF-κB-luciferase (NF-κB-luc) in HAECT-1 cells.

Keywords:

WAY-204688