2. Apoptosis
  3. Ferroptosis
  4. 83730-53-4

83730-53-4

L-Buthionine-(S,R)-sulfoximine Chemical Structure

83730-53-4

Chemical Structure

  • L-Buthionine-(S,R)-sulfoximine
  • Synonym(s): L-Buthionine sulfoximine; L-BSO
  • CAS No: 83730-53-4
    Formula: C8H18N2O3S
    Molecular Weight: 222.31
  • IUPAC Name: (2S)-2-amino-4-(butylsulfonimidoyl)butanoic acid
  • InChIKey: KJQFBVYMGADDTQ-CVSPRKDYSA-N
  • SMILES: N[C@H](C(O)=O)CCS(CCCC)(=O)=N

Biological Activity: L-Buthionine-(S,R)-sulfoximine is a cell-permeable, potent, fast acting and irreversible inhibitor of g-glutamylcysteine synthetase and depletes cellular glutathione levels. The IC50 value of L-Buthionine-(S,R)-sulfoximine on melanoma, breast and ovarian tumor specimens are 1.9 μM, 8.6 μM, and 29 μM, respectively.

Cat. No. Product Name Purity Description
HY-106376A L-Buthionine-(S,R)-sulfoximine 99.35% L-Buthionine-(S,R)-sulfoximine is a cell-permeable, potent, fast acting and irreversible inhibitor of g-glutamylcysteine synthetase and depletes cellular glutathione levels. The IC50 value of L-Buthionine-(S,R)-sulfoximine on melanoma, breast and ovarian tumor specimens are 1.9 μM, 8.6 μM, and 29 μM, respectively.

Keywords:

L-Buthionine-(S,R)-sulfoximine