2. GPCR/G Protein Neuronal Signaling
  3. Dopamine Receptor
  4. 846032-02-8

846032-02-8

PF-00217830 Chemical Structure

846032-02-8

Chemical Structure

  • PF-00217830
  • CAS No: 846032-02-8
    Formula: C26H30N4O2
    Molecular Weight: 430.54
  • IUPAC Name: 7-(4-(4-(naphthalen-1-yl)piperazin-1-yl)butoxy)-4,8-dihydro-1,8-naphthyridin-2(3H)-one
  • InChIKey: QGNOXTFZOLDODX-UHFFFAOYSA-N
  • SMILES: O=C1N=C2NC(OCCCCN3CCN(CC3)C4=C5C=CC=CC5=CC=C4)=CC=C2CC1

Biological Activity: F-00217830 is an agonist ofDopamine D2 receptor. PF-00217830 inhibits of spontaneous locomotor activity and 2,5-dimethoxy-4-iodoamphetamine-induced head twitches in rats[1].

Cat. No. Product Name Purity Description
HY-121775 PF-00217830 F-00217830 is an agonist ofDopamine D2 receptor. PF-00217830 inhibits of spontaneous locomotor activity and 2,5-dimethoxy-4-iodoamphetamine-induced head twitches in rats.

References

[1]. Johnson DS, et al. Discovery of PF-00217830: aryl piperazine napthyridinones as D2 partial agonists for schizophrenia and bipolar disorder. Bioorg Med Chem Lett. 2011;21(9):2621-2625. [Content Brief]

Keywords:

PF-00217830