2. Anti-infection
  3. Antibiotic Bacterial
  4. 84880-03-5

84880-03-5

Cefpimizole Chemical Structure

84880-03-5

Chemical Structure

  • Cefpimizole
  • Synonym(s): U-63196E; AC-1370
  • CAS No: 84880-03-5
    Formula: C28H26N6O10S2
    Molecular Weight: 670.67
  • IUPAC Name: (6R,7R)-7-((R)-2-(4-carboxy-1H-imidazole-5-carboxamido)-2-phenylacetamido)-8-oxo-3-((4-(2-sulfoethyl)pyridin-1-ium-1-yl)methyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
  • InChIKey: LNZMRLHZGOBKAN-KAWPREARSA-N
  • SMILES: [O-]C(C1=C(C[N+]2=CC=C(CCS(=O)(O)=O)C=C2)CS[C@@]([C@@H]3NC([C@@H](C4=CC=CC=C4)NC(C5=C(N=CN5)C(O)=O)=O)=O)([H])N1C3=O)=O

Biological Activity: Cefpimizole (U-63196E) is a broad-spectrum cephalosporin antibiotic. Cefpimizole inhibits many Ampicillin (HY-B0522)-resistant bacteria, and is active against gram-negative species. Cefpimizole augments phagocytosis of macrophages and neutrophils[1][2].

Cat. No. Product Name Purity Description
HY-106350 Cefpimizole Cefpimizole (U-63196E) is a broad-spectrum cephalosporin antibiotic. Cefpimizole inhibits many Ampicillin (HY-B0522)-resistant bacteria, and is active against gram-negative species. Cefpimizole augments phagocytosis of macrophages and neutrophils.

References

[1]. Neu HC, et al. In vitro activity and beta-lactamase stability of U-63196E, a novel cephalosporin. Antimicrob Agents Chemother. 1983 Sep;24(3):375-82. [Content Brief]
[2]. Ohnishi H, et al. Effects of AC-1370, a new semisynthetic cephalosporin, on phagocyte functions. Antimicrob Agents Chemother. 1983 Jun;23(6):874-80. [Content Brief]

Keywords:

Cefpimizole