1. Anti-infection
  2. RSV
  3. 851658-28-1

851658-28-1

RSV L-protein-IN-5 Chemical Structure

851658-28-1

Chemical Structure

  • RSV L-protein-IN-5
  • CAS No: 851658-28-1
    Formula: C31H36N6O4
    Molecular Weight: 556.66
  • InChIKey: ZQJFKHMZMLDZIV-UHFFFAOYSA-N
  • SMILES: O=C1C2=C(C(C)(C)C(N1CCCNCCC3=CC=C(C(OC)=C3)OC)=O)C=C(N)C4=C2NC(C5=CC=CC(C)=N5)=N4

Biological Activity: RSV L-protein-IN-5 (compound E) is a potent inhibitor of Respiratory syncytial virus (RSV) (EC50=0.1 μM). RSV L-protein-IN-5 inhibits Polymerase (IC50=0.66 μM),and blocks RSV mRNA synthesis by inhibiting guanylation of viral transcripts. RSV L-protein-IN-5 shows moderate cytotoxicity (CC50=10.7 μM,HEp-2),also exhibits activity and lowers virus titers in mouse models of RSV infection[1].

Cat. No. Product Name Purity Description
HY-154968 RSV L-protein-IN-5 RSV L-protein-IN-5 (compound E) is a potent inhibitor of Respiratory syncytial virus (RSV) (EC50=0.1 μM). RSV L-protein-IN-5 inhibits Polymerase (IC50=0.66 μM),and blocks RSV mRNA synthesis by inhibiting guanylation of viral transcripts. RSV L-protein-IN-5 shows moderate cytotoxicity (CC50=10.7 μM,HEp-2),also exhibits activity and lowers virus titers in mouse models of RSV infection.

References

Keywords:

RSV L-protein-IN-5