2. Anti-infection
  3. Bacterial
  4. 864941-32-2

864941-32-2

TCA1 Chemical Structure

864941-32-2

Chemical Structure

  • TCA1
  • CAS No: 864941-32-2
    Formula: C16H13N3O4S2
    Molecular Weight: 375.42
  • IUPAC Name: ethyl (2-(benzo[d]thiazole-2-carboxamido)thiophene-3-carbonyl)carbamate
  • InChIKey: ISNBJLXHBBZKSL-UHFFFAOYSA-N
  • SMILES: O=C(NC1=C(C(NC(OCC)=O)=O)C=CS1)C2=NC3=CC=CC=C3S2

Biological Activity: TCA1 is a small molecule with activity against agent-susceptible and -resistant Mycobacterium tuberculosis (Mtb). TCA1 inhibits enzymes involved in cell wall and molybdenum cofactor biosynthesis, such as DprE1 and MoeW[1].

Cat. No. Product Name Purity Description
HY-12904 TCA1 98.29% TCA1 is a small molecule with activity against agent-susceptible and -resistant Mycobacterium tuberculosis (Mtb). TCA1 inhibits enzymes involved in cell wall and molybdenum cofactor biosynthesis, such as DprE1 and MoeW.

References

[1]. Feng Wang, et al. Identification of a small molecule with activity against drug-resistant and persistent tuberculosis. Proc Natl Acad Sci U S A. 2013 Jul 2;110(27):E2510-7. [Content Brief]

Keywords:

TCA1