2. Others Metabolic Enzyme/Protease
  3. Drug Metabolite Isotope-Labeled Compounds
  4. 866864-06-4

866864-06-4

Mono(5-carboxy-2-ethylpentyl) phthalate-d<sub>4</sub> Chemical Structure

866864-06-4

Chemical Structure

  • Mono(5-carboxy-2-ethylpentyl) phthalate-d4
  • Synonym(s): MECPP-d4
  • CAS No: 866864-06-4
    Formula: C16H16D4O6
    Molecular Weight: 312.35
  • IUPAC Name: 2-(((5-carboxy-2-ethylpentyl)oxy)carbonyl)benzoic-3,4,5,6-d4 acid
  • InChIKey: XFGRNAPKLGXDGF-KNIGXJNHSA-N
  • SMILES: OC(CCCC(CC)COC(C1=C(C([2H])=C([2H])C([2H])=C1[2H])C(O)=O)=O)=O

Biological Activity: Mono(5-carboxy-2-ethylpentyl) phthalate-d4 (MECPP-d4) is a deuterium labeled Mono(5-carboxy-2-ethylpentyl) phthalate (HY-133675). Mono(5-carboxy-2-ethylpentyl) phthalate (MECPP) is a metabolite of Di-(2-ethylhexyl) phthalate (DEHP). Di(2-ethylhexyl) phthalate is the predominant plasticizer added to rigid polyvinyl chloride (PVC) to impart flexibility, temperature tolerance, optical clarity, strength and resistance to kinking[1][2][3].

Cat. No. Product Name Purity Description
HY-133675S Mono(5-carboxy-2-ethylpentyl) phthalate-d4 Mono(5-carboxy-2-ethylpentyl) phthalate-d4 (MECPP-d4) is a deuterium labeled Mono(5-carboxy-2-ethylpentyl) phthalate (HY-133675). Mono(5-carboxy-2-ethylpentyl) phthalate (MECPP) is a metabolite of Di-(2-ethylhexyl) phthalate (DEHP). Di(2-ethylhexyl) phthalate is the predominant plasticizer added to rigid polyvinyl chloride (PVC) to impart flexibility, temperature tolerance, optical clarity, strength and resistance to kinking.
HY-133675 Mono(5-carboxy-2-ethylpentyl) phthalate 97.44% Mono(5-carboxy-2-ethylpentyl) phthalate (MECPP) is a metabolite of Di-(2-ethylhexyl) phthalate (DEHP). Di(2-ethylhexyl) phthalate is the predominant plasticizer added to rigid polyvinyl chloride (PVC) to impart flexibility, temperature tolerance, optical clarity, strength and resistance to kinking.

References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-246. [Content Brief]
[2]. Sjöberg P, et al. Effects of di-(2-ethylhexyl) phthalate and five of its metabolites on rat testis in vivo and in in vitro. Acta Pharmacol Toxicol (Copenh). 1986;58(3):225-233. [Content Brief]
[3]. Van Vliet ED, et al. A review of alternatives to di (2-ethylhexyl) phthalate-containing medical devices in the neonatal intensive care unit [published correction appears in J Perinatol. 2012 Aug;32(8):648]. J Perinatol. 2011;31(8):551-560. [Content Brief]

Keywords:

Mono(5-carboxy-2-ethylpentyl) phthalate-d4Mono(5-carboxy-2-ethylpentyl) phthalate