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  4. 208109-38-0

208109-38-0

F 13714 Chemical Structure

208109-38-0

Chemical Structure

  • F 13714
  • Synonym(s): F 14679
  • CAS No: 208109-38-0
    Formula: C21H25ClF2N4O
    Molecular Weight: 422.90
  • IUPAC Name: (3-chloro-4-fluorophenyl)(4-fluoro-4-((((5-methyl-6-(methylamino)pyridin-2-yl)methyl)amino)methyl)piperidin-1-yl)methanone
  • InChIKey: QILKJZOYDVAGPZ-UHFFFAOYSA-N
  • SMILES: O=C(C1=CC(Cl)=C(F)C=C1)N2CCC(CNCC3=CC=C(C)C(NC)=N3)(F)CC2

Biological Activity: F 13714 (F 14679) is a prototypical 5-HT1A agonist with a pKi of 10.23. F 13714 induces large Ca2+ responses[1].

Cat. No. Product Name Purity Description
HY-146232 F 13714 F 13714 (F 14679) is a prototypical 5-HT1A agonist with a pKi of 10.23. F 13714 induces large Ca2+ responses.

References

[1]. Pauwels PJ, et al. Ca2+ responses in Chinese hamster ovary-K1 cells demonstrate an atypical pattern of ligand-induced 5-HT1A receptor activation. J Pharmacol Exp Ther. 2003 Nov;307(2):608-14. [Content Brief]

Keywords:

F 13714