2. Neuronal Signaling
  3. Amyloid-β
  4. 868592-56-7

868592-56-7

NIAD-4 Chemical Structure

868592-56-7

Chemical Structure

  • NIAD-4
  • CAS No: 868592-56-7
    Formula: C18H10N2OS2
    Molecular Weight: 334.41
  • IUPAC Name: 2-((5'-(4-hydroxyphenyl)-[2,2'-bithiophen]-5-yl)methylene)malononitrile
  • InChIKey: KLFRZDOQQDHVSS-UHFFFAOYSA-N
  • SMILES: N#C/C(C#N)=C/C1=CC=C(C2=CC=C(C3=CC=C(O)C=C3)S2)S1

Biological Activity: NIAD-4 is a fluorophore for optical imaging of amyloid-β (Aβ) in the central nervous system (CNS) for Alzheimer’s disease (AD). NIAD-4 binds to the same Aβ site with the binding affinity (Ki) of 10 nM[1].

Cat. No. Product Name Purity Description
HY-111263 NIAD-4 99.11% NIAD-4 is a fluorophore for optical imaging of amyloid-β (Aβ) in the central nervous system (CNS) for Alzheimer’s disease (AD). NIAD-4 binds to the same Aβ site with the binding affinity (Ki) of 10 nM.

References

[1]. Kenneth T. Cheng, et al. [[5'-(4-Hydroxyphenyl)[2,2’-bithiophen]-5-yl]methylene]-propanedinitrile NIAD-4.

Keywords:

NIAD-4