2. Immunology/Inflammation
  3. Toll-like Receptor (TLR)
  4. 872178-65-9

872178-65-9

Rabeximod Chemical Structure

872178-65-9

Chemical Structure

  • Rabeximod
  • Synonym(s): ROB-803
  • CAS No: 872178-65-9
    Formula: C22H24ClN5O
    Molecular Weight: 409.91
  • IUPAC Name: 2-(9-chloro-2,3-dimethyl-6H-indolo[2,3-b]quinoxalin-6-yl)-N-(2-(dimethylamino)ethyl)acetamide
  • InChIKey: PDNNUMNEXITLCZ-UHFFFAOYSA-N
  • SMILES: O=C(CN1C2=NC3=C(N=C2C4=C1C=CC(Cl)=C4)C=C(C)C(C)=C3)NCCN(C)C

Biological Activity: Rabeximod (ROB-803), an anti-rheumatic compound, impairs the differentiation and function of human pro-inflammatory dendritic cells and macrophages via downregulating TLR2 and TLR4 stimulation. Rabeximod (ROB-803) is used for rheumatoid arthritis (RA) research[1].

Cat. No. Product Name Purity Description
HY-14750 Rabeximod Rabeximod (ROB-803), an anti-rheumatic compound, impairs the differentiation and function of human pro-inflammatory dendritic cells and macrophages via downregulating TLR2 and TLR4 stimulation. Rabeximod (ROB-803) is used for rheumatoid arthritis (RA) research.

References

[1]. Pablo Giusti, et al. The novel anti-rheumatic compound Rabeximod impairs differentiation and function of human pro-inflammatory dendritic cells and macrophages. Immunobiology. 2011 Jan-Feb;216(1-2):243-50. [Content Brief]

Keywords:

Rabeximod