2. Protein Tyrosine Kinase/RTK
  3. Bcr-Abl
  4. 131780-48-8

131780-48-8

DAU 5884 hydrochloride Chemical Structure

131780-48-8

Chemical Structure

  • DAU 5884 hydrochloride
  • CAS No: 131780-48-8
    Formula: C17H22ClN3O3
    Molecular Weight: 351.83
  • IUPAC Name: (1R,3r,5S)-8-methyl-8-azabicyclo[3.2.1]octan-3-yl 2-oxo-1,4-dihydroquinazoline-3(2H)-carboxylate hydrochloride
  • InChIKey: FDERDDSQHZRNGC-MGMJSKNASA-N
  • SMILES: CN([C@@H](CC1)C2)[C@H]1C[C@@H]2OC(N3CC4=CC=CC=C4NC3=O)=O.Cl

Biological Activity: DAU 5884 hydrochloride is a potent muscarinic M3 receptor antagonist. DAU 5884 hydrochloride inhibits methacholine-dependent effects on cell proliferation and muscle contractility[1].

Cat. No. Product Name Purity Description
HY-107645 DAU 5884 hydrochloride ≥99.0% DAU 5884 hydrochloride is a potent muscarinic M3 receptor antagonist. DAU 5884 hydrochloride inhibits methacholine-dependent effects on cell proliferation and muscle contractility.

References

[1]. Gosens R, et, al. Muscarinic M3-receptors mediate cholinergic synergism of mitogenesis in airway smooth muscle. Am J Respir Cell Mol Biol. 2003 Feb;28(2):257-62. [Content Brief]

Keywords:

DAU 5884 hydrochloride