2. Apoptosis Autophagy
  3. Bcl-2 Family Autophagy
  4. 496801-51-5

496801-51-5

OH-C-Chol Chemical Structure

496801-51-5

Chemical Structure

  • OH-C-Chol
  • CAS No: 496801-51-5
    Formula: C32H56N2O3
    Molecular Weight: 516.80
  • InChIKey: IVKGTZVIOSLOAM-PTHRTHQKSA-N
  • SMILES: C[C@@]12[C@]3([H])[C@](CC=C1C[C@H](CC2)OC(NCCNCCO)=O)([H])[C@@]4([H])[C@](CC3)([C@@](CC4)([H])[C@H](C)CCCC(C)C)C

Biological Activity: OH-C-Chol is a cationic liposome that serves as a siRNA delivery vehicle. OH-C-Chol (LP-C) and OH-NC-Chol (LP-NC)/siRNA complexes (lipoplexes) showed better performance than NP-C and NP-NC/siRNA complexes (nanocomplexes), respectively. ) greater gene silencing effect[1].

Cat. No. Product Name Purity Description
HY-160581 OH-C-Chol OH-C-Chol is a cationic liposome that serves as a siRNA delivery vehicle. OH-C-Chol (LP-C) and OH-NC-Chol (LP-NC)/siRNA complexes (lipoplexes) showed better performance than NP-C and NP-NC/siRNA complexes (nanocomplexes), respectively. ) greater gene silencing effect.

References

[1]. Hattori Y, et al. siRNA delivery into tumor cells by cationic cholesterol derivative-based nanoparticles and liposomes. Biol Pharm Bull. 2015;38(1):30-8. [Content Brief]

Keywords:

OH-C-Chol