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  5. 56317-21-6

56317-21-6

Moracin M Chemical Structure

56317-21-6

Chemical Structure

  • Moracin M
  • CAS No: 56317-21-6
    Formula: C14H10O4
    Molecular Weight: 242.23
  • IUPAC Name: 5-(6-hydroxybenzofuran-2-yl)benzene-1,3-diol
  • InChIKey: LHPRYOJTASOZGJ-UHFFFAOYSA-N
  • SMILES: OC1=CC(C2=CC3=CC=C(O)C=C3O2)=CC(O)=C1

Biological Activity: Moracin M is a phenolic component that can be isolated from Mori Cortex, is a potent phosphodiesterase-4 (PDE4) inhibitor with IC50 values of 2.9, 4.5, >40, and >100 μM for PDE4D2, PDE4B2, PDE5A1, and PDE9A2, respectively. Moracin M has anti-inflammatory activity[1][2].

Cat. No. Product Name Purity Description
HY-122942 Moracin M 98.90% Moracin M is a phenolic component that can be isolated from Mori Cortex, is a potent phosphodiesterase-4 (PDE4) inhibitor with IC50 values of 2.9, 4.5, >40, and >100 μM for PDE4D2, PDE4B2, PDE5A1, and PDE9A2, respectively. Moracin M has anti-inflammatory activity.

References

[1]. Chen SK, et al. Moracin M from Morus alba L. is a natural phosphodiesterase-4 inhibitor. Bioorg Med Chem Lett. 2012 May 1;22(9):3261-4. [Content Brief]
[2]. Lee JH, et al. Moracin M inhibits airway inflammation by interrupting the JNK/c-Jun and NF-κB pathways in vitro and in vivo. Eur J Pharmacol. 2016;783:64-72. [Content Brief]

Keywords:

Moracin M