2. Cell Cycle/DNA Damage
  3. Nucleoside Antimetabolite/Analog
  4. 917110-29-3

917110-29-3

3’-Deoxy-3’-fluoro-5-methyl-xylo-uridine Chemical Structure

917110-29-3

Chemical Structure

  • 3’-Deoxy-3’-fluoro-5-methyl-xylo-uridine
  • CAS No: 917110-29-3
    Formula: C10H13FN2O5
    Molecular Weight: 260.22
  • IUPAC Name: 1-((2R,3S,4R,5R)-4-fluoro-3-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione
  • InChIKey: XFLCLDYCKOUGAR-JVZYCSMKSA-N
  • SMILES: OC[C@@H]1[C@H](F)[C@@H](O)[C@H](N(C(N2)=O)C=C(C)C2=O)O1

Biological Activity: 3’-Deoxy-3’-fluoro-5-methyl-xylo-uridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Cat. No. Product Name Purity Description
HY-152736 3’-Deoxy-3’-fluoro-5-methyl-xylo-uridine 3’-Deoxy-3’-fluoro-5-methyl-xylo-uridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.

References

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. [Content Brief]

Keywords:

3’-Deoxy-3’-fluoro-5-methyl-xylo-uridine