2. Others Cell Cycle/DNA Damage
  3. DNA Alkylator/Crosslinker Drug Derivative
  4. 14348-38-0

14348-38-0

4-Bromo-3-hydroxybenzoic acid Chemical Structure

14348-38-0

Chemical Structure

  • 4-Bromo-3-hydroxybenzoic acid
  • CAS No: 14348-38-0
    Formula: C7H5BrO3
    Molecular Weight: 217.02
  • IUPAC Name: 4-bromo-3-hydroxybenzoic acid
  • InChIKey: PAJSESFUWIYFNF-UHFFFAOYSA-N
  • SMILES: O=C(O)C1=CC=C(Br)C(O)=C1

Biological Activity: 4-Bromo-3-hydroxybenzoic acid is a metabolite of Brocresine and a histidine decarboxylase (HDC) inhibitor with IC50s of 1 mM for both rat fetal and rat gastric HDC. 4-Bromo-3-hydroxybenzoic acid also inhibits aromatic-L-amino acid decarboxylase from hog kidney and rat gastric mucosa in vitro with IC50s of 1 mM for both enzymes[1][2].

Cat. No. Product Name Purity Description
HY-W003445 4-Bromo-3-hydroxybenzoic acid 99.10% 4-Bromo-3-hydroxybenzoic acid is a metabolite of Brocresine and a histidine decarboxylase (HDC) inhibitor with IC50s of 1 mM for both rat fetal and rat gastric HDC. 4-Bromo-3-hydroxybenzoic acid also inhibits aromatic-L-amino acid decarboxylase from hog kidney and rat gastric mucosa in vitro with IC50s of 1 mM for both enzymes.

References

[1]. Ellenbogen L, et al. Studies on the inhibition of histidine decarboxylase, aromatic-L-amino acid decarboxylase and acid secretion by brocresine and its metabolites. Biochem Pharmacol. 1973 Apr 15;22(8):939-47. [Content Brief]
[2]. Qian S, et al. Inhibiting Histamine Signaling Ameliorates Vertigo Induced by Sleep Deprivation. J Mol Neurosci. 2019 Mar;67(3):411-417. [Content Brief]

Keywords:

4-Bromo-3-hydroxybenzoic acid