2. Apoptosis
  3. Ferroptosis
  4. 931704-14-2

931704-14-2

GPX4-IN-12 Chemical Structure

931704-14-2

Chemical Structure

  • GPX4-IN-12
  • CAS No: 931704-14-2
    Formula: C21H19N5O3
    Molecular Weight: 389.41
  • InChIKey: FGWJZHXATWRJIB-UHFFFAOYSA-N
  • SMILES: N#CC1=C(NCCCN2C=CN=C2)OC(C3=CC=C(O3)COC4=CC=CC=C4)=N1

Biological Activity: GPX4-IN-12 (compound I22) is a non-covalent GPX4 inhibitor. GPX4-IN-12 induces ferroptosis and inhibits cell growth of HT1080 cells[1].

Cat. No. Product Name Purity Description
HY-162718 GPX4-IN-12 GPX4-IN-12 (compound I22) is a non-covalent GPX4 inhibitor. GPX4-IN-12 induces ferroptosis and inhibits cell growth of HT1080 cells.

References

[1]. Huang W, et al. Ferroptosis-inducing compounds synergize with docetaxel to overcome chemoresistance in docetaxel-resistant non-small cell lung cancer cells. Eur J Med Chem. 2024 Jul 10;276:116670. [Content Brief]

Keywords:

GPX4-IN-12