2. Anti-infection
  3. Bacterial Antibiotic
  4. 934628-27-0

934628-27-0

Nilofabicin Chemical Structure

934628-27-0

Chemical Structure

  • Nilofabicin
  • Synonym(s): CG-400549
  • CAS No: 934628-27-0
    Formula: C19H20N2O2S
    Molecular Weight: 340.44
  • IUPAC Name: 1-(3-amino-2-methylbenzyl)-4-(2-(thiophen-2-yl)ethoxy)pyridin-2(1H)-one
  • InChIKey: YCLREGRRHGLOAK-UHFFFAOYSA-N
  • SMILES: O=C1C=C(OCCC2=CC=CS2)C=CN1CC3=CC=CC(N)=C3C

Biological Activity: Nilofabicin is an enoyl-(acyl-carrier protein) reductase (FabI) inhibitor. Nilofabicin had an MIC(90) of 0.5 microg/ml for Staphylococcus aureus strains and was more potent than either linezolid or vancomycin[1].

Cat. No. Product Name Purity Description
HY-111071 Nilofabicin 99.58% Nilofabicin is an enoyl-(acyl-carrier protein) reductase (FabI) inhibitor. Nilofabicin had an MIC(90) of 0.5 microg/ml for Staphylococcus aureus strains and was more potent than either linezolid or vancomycin.
HY-111071R Nilofabicin (Standard) gamma-Valerolactone (Standard) is the analytical standard of gamma-Valerolactone. This product is intended for research and analytical applications. 5-Methyldihydrofuran-2(3H)-one is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

References

[1]. Jong Hwa Yum,et, al. In Vitro Activities of CG400549, a Novel FabI Inhibitor, against Recently Isolated Clinical Staphylococcal Strains in Korea. Antimicrob Agents Chemother. 2007 Jul; 51(7): 2591–2593.

Keywords:

NilofabicinNilofabicin (Standard)