2. Apoptosis
  3. Apoptosis
  4. 23554-99-6

23554-99-6

HOE 32020 Chemical Structure

23554-99-6

Chemical Structure

  • HOE 32020
  • CAS No: 23554-99-6
    Formula: C25H23ClN6
    Molecular Weight: 442.94
  • IUPAC Name: 2'-(4-chlorophenyl)-5-(4-methylpiperazin-1-yl)-1H,1'H-2,5'-bibenzo[d]imidazole
  • InChIKey: QXGLWDFFMBHOFL-UHFFFAOYSA-N
  • SMILES: CN1CCN(C2=CC=C3C(N=C(C4=CC=C5C(N=C(C6=CC=C(Cl)C=C6)N5)=C4)N3)=C2)CC1

Biological Activity: HOE 32020 is a marker dye in Hoechst series. Hoechst is A live nuclear marker dye. Hoechst binds to the grooves in the DNA double strand, which tends to be A/ T-rich DNA strand. Although it binds to all nucleic acids, the A/ T-rich double strand DNA significantly enhances fluorescence intensity Therefore,Hoechst dye can be used for living cell labeling. The fluorescence intensity of Hoechst dye increases with the increase of pH of solution[1].

Cat. No. Product Name Purity Description
HY-129605 Ferulenol ≥99.0% Ferulenol, a sesquiterpene prenylated coumarin derivative, specifically inhibits succinate ubiquinone reductase at the level of the ubiquinonecycle. Ferulenol shows good antimycobacterial activity and haemorrhagic action.

References

[1]. Latt SA, Stetten G, Juergens LA, Recent developments in the detection of deoxyribonucleic acid synthesis by 33258 Hoechst fluorescence. The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 23 (7): 493-505. [Content Brief]

Keywords:

HOE 32020