2. Metabolic Enzyme/Protease Apoptosis
  3. Endogenous Metabolite Apoptosis
  4. 473-90-5

473-90-5

Mesoxalate Chemical Structure

473-90-5

Chemical Structure

  • Mesoxalate
  • Synonym(s): Ketomalonic acid; Mesoxalic acid; Oxomalonic acid
  • CAS No: 473-90-5
    Formula: C3H2O5
    Molecular Weight: 118.04
  • IUPAC Name: 2-oxomalonic acid
  • InChIKey: XEEVLJKYYUVTRC-UHFFFAOYSA-N
  • SMILES: O=C(C(C(O)=O)=O)O

Biological Activity: Mesoxalate (Ketomalonic acid) a dicarboxylic acid and a ketonic acid which blocks HIV-1 reverse transcriptase (RT), with the IC50 of 2.2 μM[1][2].

Cat. No. Product Name Purity Description
HY-114634 Mesoxalate Mesoxalate (Ketomalonic acid) a dicarboxylic acid and a ketonic acid which blocks HIV-1 reverse transcriptase (RT), with the IC50 of 2.2 μM.

References

[1]. Jean A Bernatchez, et al. Derivatives of mesoxalic acid block translocation of HIV-1 reverse transcriptase. J Biol Chem. 2015 Jan 16;290(3):1474-84. [Content Brief]
[2]. W R Davis, et al. Inhibition of HIV-1 reverse transcriptase-catalyzed DNA strand transfer reactions by 4-chlorophenylhydrazone of mesoxalic acid. Biochemistry. 2000 Nov 21;39(46):14279-91. [Content Brief]

Keywords:

Mesoxalate