CASK-IN-1

Cat. No.: HY-115719 Purity: 99.7%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

CASK-IN-1 is a highly potent and selective CASK inhibitor with a K_d value of 0.022 μM.

For research use only. We do not sell to patients.

CASK-IN-1 Chemical Structure

CAS No. : 2755241-73-5

Size	Price	Stock
10 mg	USD 598	Ask For Quote & Lead Time

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This product is a controlled substance and not for sale in your territory.

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Purity & Documentation
References
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Description

CASK-IN-1 is a highly potent and selective CASK inhibitor with a K_d value of 0.022 μM.

Molecular Weight

610.34

Formula

C₂₄H₃₀Br₂N₆O₃

CAS No.

2755241-73-5

Appearance

Solid

Color

White to off-white

SMILES

O=C(C1=CN=C(N=C1NC2CCCC2)NCC3=CC(Br)=C(C=C3Br)C)NCCCN4CCOC4=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : 12.21 mg/mL (20.01 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	1.6384 mL	8.1922 mL	16.3843 mL
5 mM	0.3277 mL	1.6384 mL	3.2769 mL
10 mM	0.1638 mL	0.8192 mL	1.6384 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 99.7%

Select Batch:

Data Sheet (267 KB) SDS (251 KB)

COA (247 KB) Elemental Analysis Report (106 KB)

Handling Instructions (2659 KB)

References

[1]. Russ N, et al. Design and Development of a Chemical Probe for Pseudokinase Ca2+/calmodulin-Dependent Ser/Thr Kinase. J Med Chem. 2021 Oct 14;64(19):14358-14376. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	1.6384 mL	8.1922 mL	16.3843 mL	40.9608 mL
	5 mM	0.3277 mL	1.6384 mL	3.2769 mL	8.1922 mL
	10 mM	0.1638 mL	0.8192 mL	1.6384 mL	4.0961 mL
	15 mM	0.1092 mL	0.5461 mL	1.0923 mL	2.7307 mL
	20 mM	0.0819 mL	0.4096 mL	0.8192 mL	2.0480 mL

CASK-IN-1 Related Classifications

Neurological Disease

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

CASK-IN-12755241-73-5OthersInhibitorinhibitorinhibit

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