2. GPCR/G Protein Neuronal Signaling
  3. Cannabinoid Receptor
  4. CB65

CB65 is a potent and high affinity CB2 selective agonist with a Ki value of 3.3 nM. CB65 exhibits a Ki of >1000 nM for CB1 receptor.

For research use only. We do not sell to patients.

CB65 Chemical Structure

CB65 Chemical Structure

CAS No. : 913534-05-1

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5 mg USD 170 In-stock
10 mg USD 255 In-stock
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Based on 1 publication(s) in Google Scholar

CB65 Related Antibodies

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CB1 CB2

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Description

CB65 is a potent and high affinity CB2 selective agonist with a Ki value of 3.3 nM. CB65 exhibits a Ki of >1000 nM for CB1 receptor[1].

Molecular Weight

417.93

Formula

C22H28ClN3O3
CAS No.
Appearance

Solid

SMILES

O=C(NC1CCCCC1)C2=CN(C3=CC(Cl)=CC=C3C2=O)CCN4CCOCC4
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 5 mg/mL (11.96 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.3927 mL 11.9637 mL 23.9275 mL
5 mM 0.4785 mL 2.3927 mL 4.7855 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
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Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.3927 mL 11.9637 mL 23.9275 mL 59.8186 mL
5 mM 0.4785 mL 2.3927 mL 4.7855 mL 11.9637 mL
10 mM 0.2393 mL 1.1964 mL 2.3927 mL 5.9819 mL
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CB65 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

CB65913534-05-1CB 65CB-65Cannabinoid ReceptorCB2 receptorCB1 receptorInhibitorinhibitorinhibit

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