1. Metabolic Enzyme/Protease
  2. E1/E2/E3 Enzyme
  3. Cbl-b-IN-17

Cbl-b-IN-17 (Example-40) is an inhibitor of Cbl-b with an IC50 value <100 nM.

For research use only. We do not sell to patients.

Cbl-b-IN-17 Chemical Structure

Cbl-b-IN-17 Chemical Structure

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Description

Cbl-b-IN-17 (Example-40) is an inhibitor of Cbl-b with an IC50 value <100 nM[1].

IC50 & Target

IC50: <100 nM (Cbl-b)[1].

Molecular Weight

524.58

Formula

C28H31F3N6O

SMILES

O=C1N(C2=CC=CC(C(C3CCC3)C4=NN=CN4C)=C2)C=NC5=C1C=C(CNCC(C)C)C=C5C(F)(F)F

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Cbl-b-IN-17
Cat. No.:
HY-158171
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