2. Epigenetics
  3. Epigenetic Reader Domain Histone Acetyltransferase
  4. CBP/p300-IN-15

CBP/p300-IN-15 (compound 13a) is a potent p300/CBP inhibitor, with IC50 values of 2.50 and 28.0 nM, respectively. CBP/p300-IN-15 shows good activity against OVCAR-3 and A2780 cell line, with EC50 values of 0.865 and 2.71 μM, respectively. CBP/p300-IN-15 can be used for ovarian cancer research.

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CBP/p300-IN-15 Chemical Structure

CBP/p300-IN-15 Chemical Structure

CAS No. : 2379409-91-1

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CBP/p300-IN-15 Related Antibodies

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Description

CBP/p300-IN-15 (compound 13a) is a potent p300/CBP inhibitor, with IC50 values of 2.50 and 28.0 nM, respectively. CBP/p300-IN-15 shows good activity against OVCAR-3 and A2780 cell line, with EC50 values of 0.865 and 2.71 μM, respectively. CBP/p300-IN-15 can be used for ovarian cancer research[1].

IC50 & Target

CBP

28 nM (IC50)

p300

2.5 nM (IC50)

Molecular Weight

476.52

Formula

C26H28N4O5
CAS No.
SMILES

CNC(NC1=CC=C2C(CC[C@@]23OC(N(C3=O)CC(N4CC5=CC=CC=C5CC[C@H]4C)=O)=O)=C1)=O
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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CBP/p300-IN-15 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

CBP/p300-IN-152379409-91-1Epigenetic Reader DomainHistone AcetyltransferaseHATsHATEpigeneticsHistone acetyltransferaseP300/CBPOvarian cancerH3K27OVCAR-3A2780Inhibitorinhibitorinhibit

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