2. Cell Cycle/DNA Damage
  3. Polo-like Kinase (PLK)
  4. CD 10899

CD 10899 is a hydroxylated metabolite of Volasertib (HY-12137). CD 10899 is pharmacologically active against Polo-like kinase 1 (PLK1) (IC50: 6 nM). Volasertib is an orally active, highly potent and ATP-competitive PLK1 inhibitor. CD 10899 can be used for research of cancer.

For research use only. We do not sell to patients.

CD 10899 Chemical Structure

CD 10899 Chemical Structure

CAS No. : 1331770-20-7

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CD 10899 Related Antibodies

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Description

CD 10899 is a hydroxylated metabolite of Volasertib (HY-12137). CD 10899 is pharmacologically active against Polo-like kinase 1 (PLK1) (IC50: 6 nM). Volasertib is an orally active, highly potent and ATP-competitive PLK1 inhibitor. CD 10899 can be used for research of cancer[1].

Molecular Weight

634.81

Formula

C34H50N8O4
CAS No.
SMILES

CC(N1C2=NC(NC3=C(C=C(C=C3)C(N[C@H]4CC[C@H](N5CCN(CC5)CC6CC6)CC4)=O)OC)=NC=C2N(C(C1(O)CC)=O)C)C
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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CD 10899 Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

CD 108991331770-20-7CD10899CD-10899Polo-like Kinase (PLK)cancerInhibitorinhibitorinhibit

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