1. Cell Cycle/DNA Damage Metabolic Enzyme/Protease
  2. CDK Carbonic Anhydrase
  3. CDK2-IN-11

CDK2-IN-11 (compound 9d) is a potent CDK2 inhibitor with an IC50 of 6.4 μM, and KI values of 23.4 nM, 56.3 nM and 44.3 nM for hCA II, hCA IX and hCA XII, respectively. CDK2-IN-11 can be used for researching anticancer.

For research use only. We do not sell to patients.

CDK2-IN-11 Chemical Structure

CDK2-IN-11 Chemical Structure

CAS No. : 2410402-82-1

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Description

CDK2-IN-11 (compound 9d) is a potent CDK2 inhibitor with an IC50 of 6.4 μM, and KI values of 23.4 nM, 56.3 nM and 44.3 nM for hCA II, hCA IX and hCA XII, respectively. CDK2-IN-11 can be used for researching anticancer[1].

IC50 & Target

IC50: 6.4 μM (CDK2)[1]
KI: 23.4 nM (hCA II), 56.3 nM (hCA IX), 44.3 nM (hCA XII)[1]

Molecular Weight

427.87

Formula

C18H14ClN7O2S

CAS No.
SMILES

O=S(C1=CC=C(/N=N/C2=C3N=CC=C(C4=CC=C(Cl)C=C4)N3N=C2N)C=C1)(N)=O

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Room temperature in continental US; may vary elsewhere.

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Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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CDK2-IN-11
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HY-150572
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