2. Metabolic Enzyme/Protease
  3. Ser/Thr Protease
  4. CE-2072

CE-2072 is an inhibitor of serine proteases neutrophil elastase and proteinase-3. CE-2072 inhibits HIV-1 production and p24 production in response to IL-18 or NaCl in infected U1 monocytic cells, reduces virus replication in infected peripheral blood mononuclear cells and blocks infection of permissive HeLa cells. CE-2072 suppresses activation of the HIV-1-inducing transcription factor NF-kB in U1 cells. CE-2072 is promising for research of HIV-1-related disease.

For research use only. We do not sell to patients.

CE-2072 Chemical Structure

CE-2072 Chemical Structure

CAS No. : 208840-22-6

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CE-2072 Related Antibodies

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Description

CE-2072 is an inhibitor of serine proteases neutrophil elastase and proteinase-3. CE-2072 inhibits HIV-1 production and p24 production in response to IL-18 or NaCl in infected U1 monocytic cells, reduces virus replication in infected peripheral blood mononuclear cells and blocks infection of permissive HeLa cells. CE-2072 suppresses activation of the HIV-1-inducing transcription factor NF-kB in U1 cells. CE-2072 is promising for research of HIV-1-related disease[1].

Molecular Weight

603.71

Formula

C33H41N5O6
CAS No.
SMILES

O=C([C@H]1N(CCC1)C([C@@H](NC(OCC2=CC=CC=C2)=O)C(C)C)=O)N[C@@H](C(C)C)C(C3=NN=C(O3)CC4=CC=CC(C)=C4)=O
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Room temperature in continental US; may vary elsewhere.
Storage

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Purity & Documentation
References
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CE-2072 Related Classifications

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This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

CE-2072208840-22-6CE2072CE 2072Ser/Thr ProteaseSerine proteasesSerine endopeptidasesThreonine proteasesserine proteases neutrophil elastaseproteinase-3HIV-1p24U1 monocytic cellsperipheral blood mononuclear cellsHeLa cellsNF-kBHIV-1-related diseaseInhibitorinhibitorinhibit

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