2. Epigenetics
  3. Epigenetic Reader Domain
  4. CEM114

CEM114 is an effective chemical epigenetic modifier (CEM) that recruits endogenous chromatin machinery.

For research use only. We do not sell to patients.

CEM114 Chemical Structure

CEM114 Chemical Structure

CAS No. : 2279062-54-1

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CEM114 Related Antibodies

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Description

CEM114 is an effective chemical epigenetic modifier (CEM) that recruits endogenous chromatin machinery[1].

In Vitro

CEM114 (200 nM; 48 hours) treatment significantly activates the Green Fluorescent Protein (GFP) signal, suggesting that excess FK506 is able to outcompete CEM114 from the FKBP binding site[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

CEM114 Related Antibodies

Cell Viability Assay[1]

Cell Line: HEK 293T cells
Concentration: 200 nM
Incubation Time: 48 hours
Result: Significantly activated the GFP signal.
Molecular Weight

1612.98

Formula

C84H122FN9O19S
CAS No.
SMILES

CC1=NOC(C)=C1C2=CC=C(C3=C2)N(C(CCC(C=C4)=CC(F)=C4OCC(N=N5)=CN5CCOCCOCCOCCNC(CCSCCC[C@H](/C=C(C[C@@H](C[C@@H]([C@](O[C@]6(C7=O)O)([H])[C@H](C[C@H]6C)OC)OC)C)\C)C(C[C@@H]([C@H]([C@H](OC([C@@](CCCC8)([H])N8C7=O)=O)/C(C)=C/[C@H](CC[C@H]9O)C[C@H]9OC)C)O)=O)=O)=N3)CCN%10CCOCC%10
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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CEM114 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

CEM1142279062-54-1CEM 114CEM-114Epigenetic Reader DomainchemicalepigeneticmodifiersrecruitendogenouschromatinmachinerysystemInhibitorinhibitorinhibit

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