2. Cell Cycle/DNA Damage
  3. Nucleoside Antimetabolite/Analog
  4. Centanamycin

Centanamycin  (Synonyms: ML-970; AS-I-145; NSC 716970)

Cat. No.: HY-160129
Handling Instructions

Molarity Calculator

Centanamycin (ML-970; AS-I-145; NSC 716970) is a novel DNA-binding agent, and shows cytotoxic activity, with an average GI50 of 34 nM in NCI-60 cell line screening.

For research use only. We do not sell to patients.

Centanamycin Chemical Structure

Centanamycin Chemical Structure

CAS No. : 413577-16-9

Size Price Stock Quantity
1 mg USD 440 Get quote 6 - 8 weeks 6 - 8 weeks 5 - 7 weeks
5 mg USD 1100 Get quote 6 - 8 weeks 6 - 8 weeks 5 - 7 weeks
10 mg USD 1750 Get quote 6 - 8 weeks 6 - 8 weeks 5 - 7 weeks
25 mg USD 3600 Get quote 6 - 8 weeks 6 - 8 weeks 5 - 7 weeks
50 mg   Get quote  
100 mg   Get quote  
Synthetic products have potential research and development risk.

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

Centanamycin Related Antibodies

Top Publications Citing Use of Products

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

Centanamycin (ML-970; AS-I-145; NSC 716970) is a novel DNA-binding agent, and shows cytotoxic activity, with an average GI50 of 34 nM in NCI-60 cell line screening[1].

Cellular Effect
Cell Line Type Value Description References
K562 IC50
0.045 μM
Compound: 11a
The concentration required for inhibiting the growth of the human K562 chronic myeloid leukemia cells by 50%
The concentration required for inhibiting the growth of the human K562 chronic myeloid leukemia cells by 50%
[PMID: 15916443]
L1210 IC50
0.18 μM
Compound: 11a
The concentration required for inhibiting the growth of the murine L1210 leukemia cells by 50%
The concentration required for inhibiting the growth of the murine L1210 leukemia cells by 50%
[PMID: 15916443]
L1210 IC50
55 nM
Compound: 6
Cytotoxicity against mouse L1210 cells after 3 days by MTT assay
Cytotoxicity against mouse L1210 cells after 3 days by MTT assay
[PMID: 20579889]
P815 IC50
0.068 μM
Compound: 4, CBI-TMI
Cytotoxicity against mouse P815 cells after 3 days
Cytotoxicity against mouse P815 cells after 3 days
[PMID: 16919946]
P815 IC50
0.068 μM
Compound: 11a
The concentration required for inhibiting the growth of the murine P815 mastocytoma cells by 50%
The concentration required for inhibiting the growth of the murine P815 mastocytoma cells by 50%
[PMID: 15916443]
Molecular Weight

453.92

Formula

C24H24ClN3O4
CAS No.
SMILES

O=C(C1=CC2=C(N1)C(OC)=C(OC)C(OC)=C2)NC3=C(CCCl)C4=C(C=CC=C4)C(N)=C3
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.

Centanamycin Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Centanamycin413577-16-9ML-970 AS-I-145 NSC 716970ML970ML 970NSC716970NSC 716970NSC-716970Nucleoside Antimetabolite/AnalogNCI-60DNA-binding agentcell cytotoxicInhibitorinhibitorinhibit

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product Name

  

Salutation

Applicant Name *

 

Email Address *

Phone Number *

 

Organization Name *

Department *

 

Requested quantity *

Country or Region *

      

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
Centanamycin
Cat. No.:
HY-160129
Quantity:
MCE Japan Authorized Agent:

Customer Review

Thank You for Your Feedback!

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

Product Name

  

Lot #

Applicant Name *

 

Email Address *

Phone Number

 

Department *

Organization Name *

 

Country or Region *

Remarks

SAFETY DATA SHEET (SDS)

English - EN (0 KB) Français - FR (0 KB) Deutsch - DE (0 KB) Norwegian - NO (0 KB) Español - ES (0 KB) Swedish - SV (0 KB)

Request for HNMR Report

We have received your request and will respond to you as soon as possible.