1. Metabolic Enzyme/Protease
  2. PCSK9
  3. Cepadacursen sodium

Cepadacursen sodium  (Synonyms: CIVI007 sodium)

Cat. No.: HY-158825
Handling Instructions

Cepadacursen sodium is a liver-targeting antisense oligonucleotide (ASO), inhibits proprotein convertase subtilisin/kexin type 9 (PCSK9) protein synthesis. Cepadacursen sodium can be used for hypercholesterolemia treatment and the prevention of atherosclerotic cardiovascular disease (ASCVD).

For research use only. We do not sell to patients.

DNA, d(P-thio)((2'-O,4'-C-methylene)rA-(2'-O,4'-C-methylene)rA-(2'-O,4'-C-methylene)m5rU-G-C-T-A-C-A-A-A-A-(2'-O,4'-C-methylene)rC-(2'-O,4'-C-methylene)m5rC-(2'-O,4'-C-methylene)m5rC-(2'-O,4'-C-methylene)rA), 5'-[O-[6-[[N2,N6-bis[2-[2-[2-[2-[[2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]ethoxy]ethoxy]ethoxy]acetyl]-L-lysyl-N6-[2-[2-[2-[2-[[2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]ethoxy]ethoxy]ethoxy]acetyl]-L-lysyl]amino]hexyl] hydrogen phosphorothioate], sodium salt (1:16)

Cepadacursen sodium Chemical Structure

CAS No. : 2252375-14-5

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Description

Cepadacursen sodium is a liver-targeting antisense oligonucleotide (ASO), inhibits proprotein convertase subtilisin/kexin type 9 (PCSK9) protein synthesis. Cepadacursen sodium can be used for hypercholesterolemia treatment and the prevention of atherosclerotic cardiovascular disease (ASCVD).

CAS No.
SMILES

[Cepadacursen (sodium)]

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Room temperature in continental US; may vary elsewhere.

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Cepadacursen sodium
Cat. No.:
HY-158825
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