2. Membrane Transporter/Ion Channel
  3. Sodium Channel
  4. Ceratotoxin-2

Ceratotoxin-2  (Synonyms: CcoTx2; β-TRTX-cm1b)

Cat. No.: HY-P5810
Handling Instructions

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Ceratotoxin-2 (CcoTx2) is a voltage-gated sodium channel blocker with IC50s of 8 nM and 88 nM against Nav1.2/β1 and Nav1.3/β1, respectively.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

Ceratotoxin-2 Chemical Structure

Ceratotoxin-2 Chemical Structure

CAS No. : 880885-98-3

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Ceratotoxin-2 Related Antibodies

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Description

Ceratotoxin-2 (CcoTx2) is a voltage-gated sodium channel blocker with IC50s of 8 nM and 88 nM against Nav1.2/β1 and Nav1.3/β1, respectively[1].

IC50 & Target

IC50: 8 nM (Nav1.2/β1), 88 nM (Nav1.3/β1), 400 nM (Nav1.4/β1), 407 nM (Nav1.1/β1), 1634 nM (Nav1.5/β1)[1]
Molecular Weight

4092.67

Formula

C177H260N52O49S6
CAS No.
Sequence

Asp-Cys-Leu-Gly-Trp-Phe-Lys-Ser-Cys-Asp-Pro-Lys-Asn-Asp-Lys-Cys-Cys-Lys-Asn-Tyr-Thr-Cys-Ser-Arg-Arg-Asp-Arg-Trp-Cys-Lys-Tyr-Tyr-Leu-NH2 (Disulfide bridge:Cys2-Cys17;Cys9-Cys22;Cys16-Cys29)
Sequence Shortening

DCLGWFKSCDPKNDKCCKNYTCSRRDRWCKYYL-NH2 (Disulfide bridge:Cys2-Cys17;Cys9-Cys22;Cys16-Cys29)
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Ceratotoxin-2 Related Classifications

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Ceratotoxin-2880885-98-3CcoTx2 β-TRTX-cm1bCeratotoxin2Ceratotoxin 2CcoTx 2CcoTx-2Sodium ChannelNa channelsNa+ channelsCeratogyrus cornuatusX. laevis oocytesInhibitorinhibitorinhibit

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