1. Metabolic Enzyme/Protease
  2. Farnesyl Transferase
  3. Chaetomellic acid A

Chaetomellic acid A can be isolated from Chaetomella acutiseta. Chaetomellic acid A is a specific inhibitor of farnesyl-protein transferase. Chaetomellic acid A decreases oxidative stress-induced apoptosis in cells. Chaetomellic acid A reduces renal damage after unilateral ureteral obstruction (UUO) in mice.

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Chaetomellic acid A Chemical Structure

Chaetomellic acid A Chemical Structure

CAS No. : 148796-51-4

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Description

Chaetomellic acid A can be isolated from Chaetomella acutiseta. Chaetomellic acid A is a specific inhibitor of farnesyl-protein transferase. Chaetomellic acid A decreases oxidative stress-induced apoptosis in cells. Chaetomellic acid A reduces renal damage after unilateral ureteral obstruction (UUO) in mice[1][2].

Molecular Weight

326.47

Formula

C19H34O4

CAS No.
SMILES

O=C(O)/C(C)=C(CCCCCCCCCCCCCC)\C(O)=O

Structure Classification
Initial Source

Chaetomella acutiseta

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Chaetomellic acid A
Cat. No.:
HY-134579
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