1. Membrane Transporter/Ion Channel
  2. Potassium Channel
  3. Chlorahololide D

Chlorahololide D is a potent and selective Potassium Channel blocker with an IC50 value of 2.7 μM. Chlorahololide D is a nature product that could be isolated from the whole plant of Chloranthus holostegius.

For research use only. We do not sell to patients.

Chlorahololide D Chemical Structure

Chlorahololide D Chemical Structure

CAS No. : 943136-39-8

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Based on 1 publication(s) in Google Scholar

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Description

Chlorahololide D is a potent and selective Potassium Channel blocker with an IC50 value of 2.7 μM. Chlorahololide D is a nature product that could be isolated from the whole plant of Chloranthus holostegius[1].

Cellular Effect
Cell Line Type Value Description References
WI-38 IC50
0.16 μM
Compound: 20
Cytotoxicity against human WI38 cells after 72 hrs by CCK8 assay
Cytotoxicity against human WI38 cells after 72 hrs by CCK8 assay
[PMID: 27997206]
Molecular Weight

676.75

Formula

C38H44O11

CAS No.
SMILES

COC(/C(C)=C1[C@]2([H])[C@@]34[C@](CC5=C2[C@]([C@@]6([H])[C@]5([H])C6)([C@H](C/1=O)O)C)([H])[C@]7([C@@]8([H])[C@]([C@](O)([C@]7([H])CC3=C(C(O4)=O)COC(C)=O)COC(/C(C)=C/C)=O)([H])C8)C)=O

Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
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    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Chlorahololide D
Cat. No.:
HY-N3573
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