1. Membrane Transporter/Ion Channel Neuronal Signaling
  2. GABA Receptor Sodium Channel Potassium Channel
  3. Cicutoxin

Cicutoxin is a convulsant. Cicutoxin blocks Na+ and K+ channels and inhibits γ-aminobutyric acid pathways. Cicutoxin is a potent GABA antagonist that induces recurrent seizures and exerts cholinergic effects. Cicutoxin acts primarily on the brain and skeletal muscles. Cicutoxin can be isolated from Cicuta maculata (water hemlock) and Cicuta douglasii.

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Cicutoxin Chemical Structure

Cicutoxin Chemical Structure

CAS No. : 505-75-9

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Description

Cicutoxin is a convulsant. Cicutoxin blocks Na+ and K+ channels and inhibits γ-aminobutyric acid pathways. Cicutoxin is a potent GABA antagonist that induces recurrent seizures and exerts cholinergic effects. Cicutoxin acts primarily on the brain and skeletal muscles. Cicutoxin can be isolated from Cicuta maculata (water hemlock) and Cicuta douglasii[1].

Molecular Weight

258.36

Formula

C17H22O2

CAS No.
SMILES

OCCCC#CC#C/C=C/C=C/C=C/[C@H](O)CCC

Structure Classification
Initial Source
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Room temperature in continental US; may vary elsewhere.

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Please store the product under the recommended conditions in the Certificate of Analysis.

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    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Cicutoxin
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HY-N15274
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