2. Apoptosis
  3. Apoptosis
  4. Cinnamic acid sodium

Cinnamic acid sodium is a orally active naturally occurring aromatic fatty acid of low toxicity. Cinnamic acid sodium shows neuroprotective and anti-inflammatory effects.

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Cinnamic acid sodium Chemical Structure

Cinnamic acid sodium Chemical Structure

CAS No. : 538-42-1

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Cinnamic acid sodium Related Antibodies

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Description

Cinnamic acid sodium is a orally active naturally occurring aromatic fatty acid of low toxicity. Cinnamic acid sodium shows neuroprotective and anti-inflammatory effects[1][2][3].

In Vitro

Cinnamic acid sodium (0.05, 0.4, 3.2 mM; 6, 12, 24 h) induces apoptosis in HT-144 cells in 3.2 mM at 24 h[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Cinnamic acid sodium Related Antibodies

Apoptosis Analysis[3]

Cell Line: NGM, HT-144 cells
Concentration: 0.05, 0.4, 3.2 mM
Incubation Time: 6, 12, 24 h
Result: Induced apoptosis in HT-144 cells in 3.2 mM at 24 h, no effect apoptosis in NGM cells.
In Vivo

Cinnamic acid sodium (100 mg/kg; gavage) activates PPARα to protect the loss of dopaminergic neurons, restore striatal fibers and neurotransmitters, and improve the behavioral functions in MPTP-intoxicated mice[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: 6-8 weeks, C57BL/6 mice (18 mg/kg MPTP-HCl, i.p.; at 2-h intervals for 4 times)[1]
Dosage: 100 mg/kg
Administration: Gavage; starting from 3 h after the last injection of MPTP
Result: Protected nigral TH levels, protected striatal innervation and neurotransmitters, restored locomotor deficit, increased the activation of Peroxisome Proliferator-Activated Receptor alpha (PPARα) in primary mouse astrocytes, protected striatal TH via PPARα.
Molecular Weight

170.14

Formula

C9H7NaO2
CAS No.
SMILES

O=C(O[Na])/C=C/C1=CC=CC=C1
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Cinnamic acid sodium Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Cinnamic acid538-42-1Apoptosisneurotransmittersanti-inflammatoryapoptosisHT-144 cellsorally activeInhibitorinhibitorinhibit

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Cinnamic acid sodium
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