1. PI3K/Akt/mTOR Apoptosis
  2. Akt MDM-2/p53
  3. cis,trans-Germacrone

cis,trans-Germacrone is a isomer of Germacrone (HY-N0440). Germacrone exhibits a wide range of antitumor, antioxidant and anti-inflammatory effects. Germacrone inhibits lung cancer cell proliferation and alters the Akt/MDM2/p53. Germacrone also arrests cell cycle at G1/S phase.

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cis,trans-Germacrone Chemical Structure

cis,trans-Germacrone Chemical Structure

CAS No. : 32663-51-7

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Description

cis,trans-Germacrone is a isomer of Germacrone (HY-N0440). Germacrone exhibits a wide range of antitumor, antioxidant and anti-inflammatory effects. Germacrone inhibits lung cancer cell proliferation and alters the Akt/MDM2/p53. Germacrone also arrests cell cycle at G1/S phase[1].

Molecular Weight

218.33

Formula

C15H22O

CAS No.
SMILES

C/C(C)=C1C(C/C(C)=C\CC/C(C)=C/C\1)=O

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
cis,trans-Germacrone
Cat. No.:
HY-145670
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