2. Others GPCR/G Protein Neuronal Signaling
  3. Isotope-Labeled Compounds 5-HT Receptor
  4. cis-Urocanic acid-13C3

cis-Urocanic acid-13C3  (Synonyms: (Z)-Urocanic acid-13C3; cis-UCA-13C3)

Cat. No.: HY-113008AS Purity: 99.46%
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cis-Urocanic acid-13C3 is the 13C-labeled cis-Urocanic acid. cis-Urocanic acid is a 5-HT2A receptor agonist. cis-Urocanic acid binds to 5-HT receptor with relatively high affinity (Kd=4.6 nM). cis-Urocanic acid is an immune modulator that induces immunosuppression by binding to the 5-HT2A receptor[1].

For research use only. We do not sell to patients.

cis-Urocanic acid-<sup>13</sup>C<sub>3</sub> Chemical Structure

cis-Urocanic acid-13C3 Chemical Structure

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Based on 1 publication(s) in Google Scholar

Other Forms of cis-Urocanic acid-13C3:

cis-Urocanic acid-13C3 Related Antibodies

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Description

cis-Urocanic acid-13C3 is the 13C-labeled cis-Urocanic acid. cis-Urocanic acid is a 5-HT2A receptor agonist. cis-Urocanic acid binds to 5-HT receptor with relatively high affinity (Kd=4.6 nM). cis-Urocanic acid is an immune modulator that induces immunosuppression by binding to the 5-HT2A receptor[1].

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

cis-Urocanic acid-13C3 Related Antibodies
Molecular Weight

139.09

Formula

C313C3H4N2O2
Unlabeled CAS

7699-35-6
Appearance

Solid

Color

White to off-white

SMILES

O=[13C](O)/[13C]=[13C]\C1=CN=CN1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

-20°C, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)

Solvent & Solubility
In Vitro: 

H2O : 50 mg/mL (359.48 mM; Need ultrasonic and warming)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 7.1896 mL 35.9479 mL 71.8959 mL
5 mM 1.4379 mL 7.1896 mL 14.3792 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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C2

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V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 7.1896 mL 35.9479 mL 71.8959 mL 179.7397 mL
5 mM 1.4379 mL 7.1896 mL 14.3792 mL 35.9479 mL
10 mM 0.7190 mL 3.5948 mL 7.1896 mL 17.9740 mL
15 mM 0.4793 mL 2.3965 mL 4.7931 mL 11.9826 mL
20 mM 0.3595 mL 1.7974 mL 3.5948 mL 8.9870 mL
25 mM 0.2876 mL 1.4379 mL 2.8758 mL 7.1896 mL
30 mM 0.2397 mL 1.1983 mL 2.3965 mL 5.9913 mL
40 mM 0.1797 mL 0.8987 mL 1.7974 mL 4.4935 mL
50 mM 0.1438 mL 0.7190 mL 1.4379 mL 3.5948 mL
60 mM 0.1198 mL 0.5991 mL 1.1983 mL 2.9957 mL
80 mM 0.0899 mL 0.4493 mL 0.8987 mL 2.2467 mL
100 mM 0.0719 mL 0.3595 mL 0.7190 mL 1.7974 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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cis-Urocanic acid-13C3 Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

cis-Urocanic acid-13C3(Z)-Urocanic acid-13C3cis-UCA-13C3Isotope-Labeled Compounds5-HT ReceptorSerotonin Receptor5-hydroxytryptamine ReceptorInhibitorinhibitorinhibit

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