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CK-3197 is a weaker inhibitor of Peak lll cyclic 3'5'-adenosine monophosphate phosphodiesterase (CAMP PDEl). CK-3197 has hemodynamic and myocardial energetic effects in vivo. CK-3197 is an imidazolone derivative used as a selective positive inotropic agent for congestive heart failure. The positive inotropy with CK-3197 is associated with small increases in heart rate (HR) without adverse effects on CBF.

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CK-3197 Chemical Structure

CK-3197 Chemical Structure

CAS No. : 132523-92-3

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Description

CK-3197 is a weaker inhibitor of Peak lll cyclic 3'5'-adenosine monophosphate phosphodiesterase (CAMP PDEl). CK-3197 has hemodynamic and myocardial energetic effects in vivo. CK-3197 is an imidazolone derivative used as a selective positive inotropic agent for congestive heart failure. The positive inotropy with CK-3197 is associated with small increases in heart rate (HR) without adverse effects on CBF[1].

Molecular Weight

402.45

Formula

C23H22N4O3

CAS No.
SMILES

O=C(C1=C(CC)NC(N1C(C2=CC=CC=C2)=O)=O)C3=CC=C(N4C(C)=NCC4)C=C3

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CK-3197 Related Classifications

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    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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CK-3197
Cat. No.:
HY-117715
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