2. Cell Cycle/DNA Damage Stem Cell/Wnt
  3. Casein Kinase
  4. CK1-IN-2 hydrochloride

CK1-IN-2 (compound Nr.4) hydrochloride is a potent CK1 inhibitor with an IC50 values of 123, 19.8, 26.8, 74.3 nM for CK1a, CK1d, CK1e, p38a, respectively.

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CK1-IN-2 hydrochloride Chemical Structure

CK1-IN-2 hydrochloride Chemical Structure

CAS No. : 1383377-49-8

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Other Forms of CK1-IN-2 hydrochloride:

CK1-IN-2 hydrochloride Related Antibodies

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Description

CK1-IN-2 (compound Nr.4) hydrochloride is a potent CK1 inhibitor with an IC50 values of 123, 19.8, 26.8, 74.3 nM for CK1a, CK1d, CK1e, p38a, respectively[1].

In Vitro

CK1-IN-2 (0.02-10 μM, 72 h) promotes myotube fusion in FSHD cells [1].
CK1-IN-2 (10 μM, 72 h) can significantly reduce the inhibitory effect of Losmapimod on myotube fusion[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

CK1-IN-2 hydrochloride Related Antibodies
Molecular Weight

345.76

Formula

C17H13ClFN3O2
CAS No.
SMILES

O=C1OCC2=NC=CC(C3=CN(C)N=C3C4=CC=C(F)C=C4)=C12.[H]Cl
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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CK1-IN-2 hydrochloride Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

CK1-IN-21383377-49-8Casein KinaseFSHDmyotube fusionInhibitorinhibitorinhibit

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