2. Others Anti-infection
  3. Isotope-Labeled Compounds Influenza Virus Parasite
  4. Cletoquine-d4

Cletoquine-d4  (Synonyms: Desethylhydroxychloroquine-d4)

Cat. No.: HY-135810S
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Cletoquine-d4 is deuterium labeled Cletoquine. Cletoquine (Desethylhydroxychloroquine) is a major active metabolite of Hydroxychloroquine. Cletoquine is produced in the liver by CYP2D6, CYP3A4, CYP3A5, and CYP2C8 isoenzymes. Cletoquine is also a Chloroquine derivative and has the ability to against the chikungunya virus (CHIKV). Cletoquine has antimalarial effects and has the potential for autoimmune diseases treatment[1][2].

For research use only. We do not sell to patients.

Cletoquine-d<sub>4</sub> Chemical Structure

Cletoquine-d4 Chemical Structure

CAS No. : 1854126-47-8

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Based on 1 publication(s) in Google Scholar

Other Forms of Cletoquine-d4:

Cletoquine-d4 Related Antibodies

Top Publications Citing Use of Products

View All Parasite Isoform Specific Products:

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Amebae Coccidia Leishmania Mite Plasmodium Toxoplasma Trypanosoma Schistosome

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Description

Cletoquine-d4 is deuterium labeled Cletoquine. Cletoquine (Desethylhydroxychloroquine) is a major active metabolite of Hydroxychloroquine. Cletoquine is produced in the liver by CYP2D6, CYP3A4, CYP3A5, and CYP2C8 isoenzymes. Cletoquine is also a Chloroquine derivative and has the ability to against the chikungunya virus (CHIKV). Cletoquine has antimalarial effects and has the potential for autoimmune diseases treatment[1][2].

IC50 & Target

Plasmodium

 

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Cletoquine-d4 Related Antibodies
Molecular Weight

311.84

Formula

C16H18D4ClN3O
CAS No.
Unlabeled CAS

4298-15-1
SMILES

[2H]C([2H])(NCCCC(NC1=CC=NC2=CC(Cl)=CC=C12)C)C([2H])(O)[2H]
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Cletoquine-d4 Related Classifications

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× = ×
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Cletoquine-d41854126-47-8Desethylhydroxychloroquine-d4Isotope-Labeled CompoundsInfluenza VirusParasiteInhibitorinhibitorinhibit

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